Know When to Use a GLP-1 Agonist or SGLT2i First-Line

You’ll hear debate about whether metformin should still be first-line for all patients with type 2 diabetes.

It continues to be the gold standard for most patients based on its established efficacy and safety...and low cost.

Metformin also has possible CV benefits...and can be used in patients with eGFR down to 30 mL/min/1.73 m².